Comment 15 for bug 1282294

And then this happened today...

apb@orange:~$ sudo apt-get upgrade
[sudo] password for apb:
Reading package lists... Done
Building dependency tree
Reading state information... Done
Calculating upgrade... Done
The following packages will be upgraded:
  adobe-flash-properties-gtk adobe-flashplugin gir1.2-gdkpixbuf-2.0
  google-chrome-stable libgdk-pixbuf2.0-0 libgdk-pixbuf2.0-0:i386
  libgdk-pixbuf2.0-common
7 upgraded, 0 newly installed, 0 to remove and 0 not upgraded.
Need to get 57.5 MB of archives.
After this operation, 2,476 kB disk space will be freed.
Do you want to continue? [Y/n]
Get:1 http://dl.google.com/linux/chrome/deb/ stable/main google-chrome-stable amd64 46.0.2490.71-1 [47.0 MB]
Get:2 http://us.archive.ubuntu.com/ubuntu/ trusty-updates/main libgdk-pixbuf2.0-0 amd64 2.30.7-0ubuntu1.2 [160 kB]
Get:3 http://archive.canonical.com/ubuntu/ trusty/partner adobe-flash-properties-gtk amd64 1:20151013.1-0trusty1 [113 kB]
Get:4 http://us.archive.ubuntu.com/ubuntu/ trusty-updates/main libgdk-pixbuf2.0-0 i386 2.30.7-0ubuntu1.2 [156 kB]
Get:5 http://archive.canonical.com/ubuntu/ trusty/partner adobe-flashplugin amd64 1:20151013.1-0trusty1 [10.1 MB]
Get:6 http://us.archive.ubuntu.com/ubuntu/ trusty-updates/main libgdk-pixbuf2.0-common all 2.30.7-0ubuntu1.2 [8,826 B]
Get:7 http://us.archive.ubuntu.com/ubuntu/ trusty-updates/main gir1.2-gdkpixbuf-2.0 amd64 2.30.7-0ubuntu1.2 [7,964 B]
Fetched 57.5 MB in 33s (1,715 kB/s)
(Reading database ... 170352 files and directories currently installed.)
Preparing to unpack .../libgdk-pixbuf2.0-0_2.30.7-0ubuntu1.2_i386.deb ...
De-configuring libgdk-pixbuf2.0-0:amd64 (2.30.7-0ubuntu1.1) ...
Unpacking libgdk-pixbuf2.0-0:i386 (2.30.7-0ubuntu1.2) over (2.30.7-0ubuntu1.1) ...
Preparing to unpack .../libgdk-pixbuf2.0-0_2.30.7-0ubuntu1.2_amd64.deb ...
Unpacking libgdk-pixbuf2.0-0:amd64 (2.30.7-0ubuntu1.2) over (2.30.7-0ubuntu1.1) ...
Preparing to unpack .../libgdk-pixbuf2.0-common_2.30.7-0ubuntu1.2_all.deb ...
Unpacking libgdk-pixbuf2.0-common (2.30.7-0ubuntu1.2) over (2.30.7-0ubuntu1.1) ...
Preparing to unpack .../google-chrome-stable_46.0.2490.71-1_amd64.deb ...
Unpacking google-chrome-stable (46.0.2490.71-1) over (45.0.2454.101-1) ...
Preparing to unpack .../adobe-flash-properties-gtk_1%3a20151013.1-0trusty1_amd64.deb ...
Unpacking adobe-flash-properties-gtk (1:20151013.1-0trusty1) over (1:20150921.1-0trusty1) ...
Preparing to unpack .../adobe-flashplugin_1%3a20151013.1-0trusty1_amd64.deb ...
Unpacking adobe-flashplugin (1:20151013.1-0trusty1) over (1:20150921.1-0trusty1) ...
Preparing to unpack .../gir1.2-gdkpixbuf-2.0_2.30.7-0ubuntu1.2_amd64.deb ...
Unpacking gir1.2-gdkpixbuf-2.0 (2.30.7-0ubuntu1.2) over (2.30.7-0ubuntu1.1) ...
Processing triggers for mime-support (3.54ubuntu1.1) ...
Processing triggers for desktop-file-utils (0.22-1ubuntu1) ...
Processing triggers for man-db (2.6.7.1-1ubuntu1) ...
Processing triggers for hicolor-icon-theme (0.13-1) ...

(gtk-update-icon-cache-3.0:14008): GdkPixbuf-WARNING **: Cannot open pixbuf loader module file '/usr/lib/x86_64-linux-gnu/gdk-pixbuf-2.0/2.10.0/loaders.cache': No such file or directory

This likely means that your installation is broken.
Try running the command
  gdk-pixbuf-query-loaders > /usr/lib/x86_64-linux-gnu/gdk-pixbuf-2.0/2.10.0/loaders.cache
to make things work again for the time being.
Setting up libgdk-pixbuf2.0-common (2.30.7-0ubuntu1.2) ...
Setting up libgdk-pixbuf2.0-0:amd64 (2.30.7-0ubuntu1.2) ...
Setting up libgdk-pixbuf2.0-0:i386 (2.30.7-0ubuntu1.2) ...
Setting up google-chrome-stable (46.0.2490.71-1) ...
Setting up adobe-flashplugin (1:20151013.1-0trusty1) ...
update-alternatives: using /usr/lib/adobe-flashplugin/libflashplayer.so to provide /usr/lib/mozilla/plugins/flashplugin-alternative.so (mozilla-flashplugin) in auto mode
Setting up adobe-flash-properties-gtk (1:20151013.1-0trusty1) ...
Setting up gir1.2-gdkpixbuf-2.0 (2.30.7-0ubuntu1.2) ...
Processing triggers for libc-bin (2.19-0ubuntu6.6) ...
apb@orange:~$ gdk-pixbuf-query-loaders > /usr/lib/x86_64-linux-gnu/gdk-pixbuf-2.0/2.10.0/loaders.cache
bash: /usr/lib/x86_64-linux-gnu/gdk-pixbuf-2.0/2.10.0/loaders.cache: Permission denied
apb@orange:~$ sudo !!
sudo gdk-pixbuf-query-loaders > /usr/lib/x86_64-linux-gnu/gdk-pixbuf-2.0/2.10.0/loaders.cache
bash: /usr/lib/x86_64-linux-gnu/gdk-pixbuf-2.0/2.10.0/loaders.cache: Permission denied
apb@orange:~$ ll /usr/lib/x86_64-linux-gnu/gdk-pixbuf-2.0/2.10.0/loaders.cache
-rw-r--r-- 1 root root 4317 Oct 14 07:08 /usr/lib/x86_64-linux-gnu/gdk-pixbuf-2.0/2.10.0/loaders.cache
apb@orange:~$ date
Wed Oct 14 07:09:38 PDT 2015
apb@orange:~$ sudo gdk-pixbuf-query-loaders
sudo: gdk-pixbuf-query-loaders: command not found
apb@orange:~$
apb@orange:~$ lsb_release
LSB Version: core-2.0-amd64:core-2.0-noarch:core-3.0-amd64:core-3.0-noarch:core-3.1-amd64:core-3.1-noarch:core-3.2-amd64:core-3.2-noarch:core-4.0-amd64:core-4.0-noarch:core-4.1-amd64:core-4.1-noarch:cxx-3.0-amd64:cxx-3.0-noarch:cxx-3.1-amd64:cxx-3.1-noarch:cxx-3.2-amd64:cxx-3.2-noarch:cxx-4.0-amd64:cxx-4.0-noarch:cxx-4.1-amd64:cxx-4.1-noarch:desktop-3.1-amd64:desktop-3.1-noarch:desktop-3.2-amd64:desktop-3.2-noarch:desktop-4.0-amd64:desktop-4.0-noarch:desktop-4.1-amd64:desktop-4.1-noarch:graphics-2.0-amd64:graphics-2.0-noarch:graphics-3.0-amd64:graphics-3.0-noarch:graphics-3.1-amd64:graphics-3.1-noarch:graphics-3.2-amd64:graphics-3.2-noarch:graphics-4.0-amd64:graphics-4.0-noarch:graphics-4.1-amd64:graphics-4.1-noarch:languages-3.2-amd64:languages-3.2-noarch:languages-4.0-amd64:languages-4.0-noarch:languages-4.1-amd64:languages-4.1-noarch:multimedia-3.2-amd64:multimedia-3.2-noarch:multimedia-4.0-amd64:multimedia-4.0-noarch:multimedia-4.1-amd64:multimedia-4.1-noarch:printing-3.2-amd64:printing-3.2-noarch:printing-4.0-amd64:printing-4.0-noarch:printing-4.1-amd64:printing-4.1-noarch:qt4-3.1-amd64:qt4-3.1-noarch:security-4.0-amd64:security-4.0-noarch:security-4.1-amd64:security-4.1-noarch
apb@orange:~$ lsb_release -rd
Description: Ubuntu 14.04.3 LTS
Release: 14.04