Comment 31 for bug 1624320

Given the number of bug reports, and that this causes delayed breakage in server environments, perhaps this bug priority should be raised from "Low" to "Medium"?

I encountered this delayed failure in an LXC container, following upgrading the server and LXC container from Ubuntu 17.10 to Ubuntu 18.04.

Workaround
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Leandro Noskoski on askubuntu.com provided this work-round.

Edit /etc/systemd/resolved.conf, adding your desired DNS server:

change this:

[Resolve]
#DNS=

to this (but use the one you want - this is an example):

[Resolve]
DNS=192.168.1.152

after that, restart the service:

service systemd-resolved restart

DNS resolving should -NOT- be broken for containers by a single version OS upgrade
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Unfortunately this is a result of systemd violating 3 of 9 tenets of the Unix Philosophy:

1 - Small is beautiful.

2 - Make each program do one thing well.

6 - Use software leverage to your advantage.